Abstract P-371

P 371 Cytogenetic studies in retinitis pigmentosa patients

The retina contains due families of phspbolipnsc C (P, 6. and u). a reccctor-activated ewYmC that PFeratcs two iolraceUuhv s%xmd n&cngcrs, diacylgly&ol md I ,$5-inositol rrispbospbale. We hnvc charactaizcd the cDNA and par&d gene sh-ucnue for human PLCB4, a p isofurm which shares uighcsr sequence homology with dx norpA PLC from Drosophila. A muwion in tie nor@ PU: leads m I retinal demmtioo m d...

C2fd20077e 371..386

The carbonate sedimentary record contains diverse compositions and textures that reflect the evolution of oceans and atmospheres through geological time. Efforts to reconstruct paleoenvironmental conditions from these deposits continue to be hindered by the need for process-based models that can explain observed shifts in carbonate chemistry and form. Traditional interpretations assume minerals...

Dmd049460 362..371

The plasma concentration of repaglinide is reported to increase greatly when given after repeated oral administration of itraconazole and gemfibrozil. The present study analyzed this interaction based on a physiologically based pharmacokinetic (PBPK) model incorporating inhibition of the hepatic uptake transporter and metabolic enzymes involved in repaglinide disposition. Firstly, the plasma co...

Bez nazwy-371

C2fd20028g 371..406

Phase separation is a fundamental phenomenon that produces spatially heterogeneous patterns in soft matter and foods. We argue that phase separation in these materials generally belongs to ‘‘viscoelastic phase separation’’, where the morphology is determined by the mechanical balance of not only the thermodynamic force (interface tension) but also the viscoelastic force. The origin of the visco...